Table 3.
Parameter | NI versus MCI | NI versus DM | NI + MCI versus DM | NI versus MCI/DM | MCI versus DM |
---|---|---|---|---|---|
Optimal cutoff | 8.5 | 6.5 | 6.5 | 7.5 | 5.5 |
AUC | 0.77 | 0.97 | 0.91 | 0.84 | 0.82 |
Accuracy | 67% | 94% | 84% | 76% | 75% |
Sensitivity | 79% | 86% | 86% | 70% | 71 |
Specificity | 58% | 75% | 84% | 82% | 77 |
MMSE accuracy (cut point <24) | 65% | 83% | 50% | 63% | 69% (cut point <20) |
Composite score (cut point < −0.33) | 71% | 91% | 83% | 72% | 62% (cut point < −0.65) |
Abbreviations: NI, no impairment; MCI, mild cognitive impairment; DM, dementia; AUC, area under the curve; MMSE, ini–Mental State Examination; SIMBAC, SIMulation-Based Assessment of Cognition.
NOTE. Composite score = average of five standardized score from RAVLT-Delayed Recall, Boston Naming Test (BNT), Digit Span Test (total of backward and forward; DST), Digit Symbol Coding (DSC), and Trail Making Test–Part B (TMT-B).