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. 2018 Mar 12;9:454. doi: 10.3389/fimmu.2018.00454

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Copyright © 2018 Pinto, Medeiros, Teixeira-Carvalho, Eloi-Santos, Fontes-Cal, Rocha, Dutra, Correa-Oliveira and Gomes.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ratio/proportion of CD80 and CD86 expression by monocytes. Ratio of CD86/CD80 expression by total monocytes (A), and proportion of these co-stimulatory molecules by the monocyte subsets (B). The groups evaluated were non-infected (NI) individuals (n = 6), indeterminate (IND, n = 10), and cardiac (CARD, n = 9) clinical forms of Chagas disease. Significant differences (p < 0.05) between groups are evidenced by lines and asterisks (*) according Kruskal–Wallis test, followed by Dunn’s post hoc test. MFI, mean fluorescence intensity.