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. 2018 Mar 16;38(2):BSR20171014. doi: 10.1042/BSR20171014

Figure 4. GAS5 inhibited the HG-induced proliferation and migration of NSCLC cells by regulating TRIB3 protein.

Figure 4

NSCLC cells were divided into five experimental groups: LG, HG, HG + pcDNA (transfection of pcDNA and HG treatment), HG + pcDNA-GAS5 (transfection of pcDNA-GAS5 and HG treatment), and HG + pcDNA-GAS5 + pcDNA-TRIB3 (co-transfection of pcDNA-GAS5 and pcDNA-TRIB3, and HG treatment). The expression of (A,B) TRIB3 protein and (C) GAS5 in NSCLC cells was measured using Western blot and qRT-PCR, respectively. The (D) proliferation and (E) migration of NSCLC cells was assessed by CCK-8 assay and Transwell system, respectively; *P<0.05 compared with LG; #P<0.05 compared with + pcDNA; &P<0.05 compared with HG + pcDNA-GAS5.