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(A–C) IL-1β, IL-10, and LDH were down-regulated after treatment with siRNA–GAS5. (D) Expression of ASC, caspase 1, procaspase 1, IL-1β, pro-IL-1β, IL-18, and pro-IL-18 were detected using Western blot. p-Cas-1 indicates procaspase 1; p-IL-1β indicates pro-IL-1β; p-IL-18 indicates pro-IL-18. *indicates P<0.05, **indicates P<0.01.
