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. 2017 Oct 12;8(12):8221–8230. doi: 10.1039/c7sc03909c

Table 2. Substrates scope varying functional groups R1 at the aromatic ring a .

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Entry Substrates Products Yield b (%)
1 graphic file with name c7sc03909c-u3.jpg graphic file with name c7sc03909c-u4.jpg 89
2 graphic file with name c7sc03909c-u5.jpg graphic file with name c7sc03909c-u6.jpg 76 (85 c ) d
3 graphic file with name c7sc03909c-u7.jpg graphic file with name c7sc03909c-u8.jpg 74 d
4 graphic file with name c7sc03909c-u9.jpg graphic file with name c7sc03909c-u10.jpg 65 d
5 graphic file with name c7sc03909c-u11.jpg graphic file with name c7sc03909c-u12.jpg 50
6 graphic file with name c7sc03909c-u13.jpg graphic file with name c7sc03909c-u14.jpg 75
7 graphic file with name c7sc03909c-u15.jpg graphic file with name c7sc03909c-u16.jpg 71

aReaction conditions: N-tosylhydrazone (1a–g) (0.1 mmol, 1.0 equiv.), LiOtBu (0.12 mmol, 1.2 equiv.), [Co(TPP)] (5 mol%), benzene (2 mL), 60 °C, overnight.

bIsolated yields after column chromatography (average of two separate experiments).

cIsolated yield of experiment performed with 1.0 mmol substrate.

dYields of these three entries based on the major E-isomer, using an E/Z-mixture containing 6–12% of the non-productive Z-isomer.