Thromboelastometry measurements after TBI demonstrate decreased platelet contribution to clot formation. Whole blood from sham and TBI mice was collected 10 min, 24 h, and 72 h after injury and was analyzed using thromboelastometry. (A) EXTEMMCF, (B) FIBTEMMCF, (C) platelet contribution to clot formation, and (D) whole blood platelet counts. Samples sizes are 8–10 for each group. Data are expressed as the mean ± standard error of the mean. *P < 0.05 based on one-way analysis of variance with Tukey post hoc test compared with sham.