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Verified specificity of lyso-Gb3 in EDTA plasma. (A) A normal volunteer, (B) an untreated female and (C) an untreated male with FD. For validation, lyso-Gb3 was used as ST while dimethyl psychosine was applied as IS. The retention time of ST (left peak) is less than that of the IS (right peak). FD, Fabry disease; lyso-Gb3, globotriaosylsphingosine; ST, standard; IS, internal standard; cps, counts per second.
