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. 2018 Feb 12;8(6):1723–1739. doi: 10.7150/thno.22056

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Effects of the treatment of B16-bearing mice with the liposomal particles. (A) Visualization of angiogenesis and cell proliferation in tumor tissue sections from mice in each treatment group by immunohistochemical staining with anti-CD31 antibody (100×, the upper panel) or anti-PCNA antibody (400×, the middle panel), respectively. Visualization of cell apoptosis in tumor tissue sections from mice in each treatment group by TUNEL (200×, the lower panel). (B) Quantitative analysis. Data are presented as the mean ± SD of each group of tumors, n = 5, *** p < 0.001.