Figure 2.

Effect of RE and metoprolol on systolic blood pressure, diastolic blood pressure, and MBP. (a) Systolic blood pressure of all groups. (b) Diastolic blood pressure of all groups. (c) Mean blood pressure of all groups. Values are expressed as the mean ± standard deviation (n = 8).^#P < 0.05,^##P < 0.01 versus normal control group; *P < 0.05, **P < 0.01 vs. model control group. SBP: Systolic blood pressure; DBP: Diastolic blood pressure; MBP: Mean blood pressure; RE: Paeoniflorin enriched extract from Radix Paeoniae alba; NC: Normal control; MC: Model control; MP-H: Metoprolol high dose (20 mg/kg, p.o.); MP-L: Metoprolol low dose (6 mg/kg, p.o.); RE-H: RE high dose (90 mg/kg, p.o.); RE-L: RE low dose (30 mg/kg, p.o.); MP + RE: metoprolol combined with RE (6 mg/kg + 30 mg/kg, p.o.)