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. 2018 Feb 20;14(53):44–52. doi: 10.4103/pm.pm_483_16

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Copyright: © 2018 Pharmacognosy Magazine

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Effect of RE and metoprolol on microcirculation. (a) Representative images of tails acquired by scanning Doppler perfusion imager. (b) Analysis laser of microvascular blood perfusion. Values are expressed as the mean ± standard deviation (n = 8).^#P < 0.05,^##P < 0.01 versus normal control group; *P < 0.05, **P < 0.01 versus MC group. RE: Paeoniflorin enriched extract from Radix Paeoniae alba; NC: Normal control; MC: Model control; MP-H: Metoprolol high dose (20 mg/kg, p.o.); MP-L: Metoprolol low dose (6 mg/kg, p.o.); RE-H: RE high dose (90 mg/kg, p.o.); RE-L: RE low dose (30 mg/kg, p.o.); MP + RE: metoprolol combined with RE (6 mg/kg + 30 mg/kg, p.o.)