Table 1.
Study Demographics
| Patient Characteristics | Total n = 265 |
European Descent n = 235 |
African Descent n=30 |
P-Value * |
|---|---|---|---|---|
| Age, median (IQR), y | 62.0 (53.0, 69.0) | 62.0 (54.5, 69.5) | 56.5 (50.2, 68.8) | 0.24 |
| Sex, Female, n (%) | 84 (31%) | 63 (26%) | 21 (70%) | 0.88 |
| BMI, median (IQR), (kg/m2)† | 27.2 (24.5, 30.3) | 27.2 (24.5, 30.3) | 26.2 (23.0, 31.6) | 0.63 |
| Diabetes, n (%)† | 35 (13%) | 28 (12%) | 7 (24%) | 0.07 |
| History of CAD, n (%)† | 160 (63%) | 143 (64%) | 17 (58%) | 0.69 |
| History of MVD, n (%)† | 136 (54%) | 114 (51%) | 22 (75%) | 0.02 |
| Hypertension, n (%)† | 137 (54%) | 115 (51%) | 22 (78%) | 0.01 |
| History of AF, n (%)† | 213 (84%) | 192 (86%) | 21 (72%) | 0.09 |
| AF Rhythm at surgery, n (%)† | 130 (51%) | 118 (53%) | 12 (41%) | 0.13 |
| Surgical Indication | ||||
| Donor, n (%) | 14 (5%) | 13 (5%) | 1 (3%) | 1.00 |
| Valve, n (%)‡ | 153 (57%) | 129 (54%) | 24 (80%) | 0.01 |
| CABG, n (%)‡ | 106 (40%) | 95 (40%) | 11 (36%) | 0.84 |
| Non-CABG Non-Valve, n (%) | 52 (19%) | 51 (21%) | 22 (73%) | <0.01 |
*
statistical significance between patients of European descent and African Descent, either by t-test, for quantitative traits, or chi-square, for categorical traits.
†
not including 1 African descent and 13 European descent donors, for which only age and sex were known.
‡
patients could have an indication for both Valve and CABG surgeries
Abbreviations used: IQR, interquartile range; BMI, body mass index; CAD, coronary artery disease; MVD, mitral valve disease; CABG, coronary artery bypass graft.