Table 1.

miRNAs targeting the mTOR pathway and cancers

miRNA	Target gene	Cancer	Function	Reference
miR-7	AKT	liver cancer	proliferation, invasion	37
miR-22	mTOR	suprarenal epithelioma	metastasis	21
miR-99	mTOR	melanoma	tumor formation	38
miR-99a	mTOR	cervical carcinoma, pancreatic cancer, esophageal squamous cell carcinoma, breast cancer	proliferation, invasion, apoptosis	39, 40
miR-99b	mTOR	pancreatic cancer	proliferation, apoptosis	41
miR-100	mTOR	bladder cancer, oophoroma, liver cancer	proliferation, cell cycle, autophagy, tumor formation	42
miR-101	EZH2	liver cancer	proliferation, invasion, cell cycle,	43
miR-125a	mTOR	liver cancer	metastasis	31
miR-125b	mTOR	sarcoma, small cell osteosarcoma	proliferation, metastasis, cell cycle, apoptosis	44, 45
miR-149	mTOR	liver cancer	proliferation	46
miR-193a-3p/5p	mTOR	NSCLC	proliferation, migration, epithelial mesenchymal transition (EMT)	47
miR-199a	mTOR	gliocytoma, endometrial cancer, liver cancer	proliferation	17
miR-204	mTOR	NSCLC, oophoroma	metastasis	48
miR-634	mTOR	cervical carcinoma	proliferation, metastasis, apoptosis	49
miR-21	TSC	gastric cancer, lymphadenoma	proliferation, cell cycle	50
miR-1271	mTOR	gastric cancer	proliferation, apoptosis	51
miR-96	mTOR	prostatic cancer	proliferation, metastasis	52
miR-155	AKT	cervical cancer	autophagy	53
miR-205	PTEN	NSCLC	proliferation, angiogenesis	18
miR-451	mTOR	colon cancer	proliferation, migration	23
miR-532-5p	mTOR	gastric cancer	proliferation, metastasis	54