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. 2018 Jan 8;9(4):674–682. doi: 10.7150/jca.22277

Figure 8.

Figure 8

Optical imaging of FITC-labeled fusion protein dFv-R-LDP in xenografted SW-1990 tumor and orthotopic Capan-2 Luc+ pancreatic cancer transplanted mice in vivo. A: targeting capability of FITC-labeled dFv-R-LDP in xenografted SW-1990 mice, the arrow indicated the location of tumor; B: targeting capability of FITC labeled dFv-R-LDP in orthotopic Capan-2 mice, the pancreatic cancer cell Capan-2 was Luc+ and orthotopic transplanted in the mice. a indicated the location of Capan-2 tumor, luciferase substrate D-luciferin (150 mg/kg) was injected intraperitoneally, and the animals were placed onto the warmed stage inside the camera box (IVIS-Imaging System, Xenogen) to locate the tumor; b: FITC-labeled dFv-R-LDP was injected via tail vein, and the graph was gotten 1 hour later after injection under the high-sensitive red-filter xenogeny system; c: the graph obtained from b, which removed the red-filter.