Table 4.

Synergistic effect of caffeine and gemcitabine or 5-FU-induced cytotoxicity in PANC-1 cells

	CDI value				CDI value
Gem (nM)	scrambled siRNA	T2R10 siRNA		5-FU (nM)	scrambled siRNA	T2R10 siRNA
1	1.09	1.00		1	1.02	1.04
10	1.03	1.02		10	1.04	1.07
100	0.94	0.88		100	1.03	1.05
1000	0.94	0.90		1000	1.00	1.02
5000	0.95	0.89		2500	0.96	1.00
10000	0.95	0.93		5000	0.93	0.95
50000	0.96	0.91		10000	0.94	0.96
100000	0.93	0.88		100000	0.92	0.91