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. 2018 Feb 14;8(7):1879–1891. doi: 10.7150/thno.22070

Figure 7.

Figure 7

Ultrasound molecular imaging assessment of atorvastatin efficacy. (A) Representative H&E images of ascending aorta sections from ApoE-/- mice fed atorvastatin or placebo in their daily hypercholesterolemic diets for 8 weeks. Scale bar = 50 μm. (B) Quantitative analysis of intima-medial thickness, with reduced intima-medial thickness in the atorvastatin-treated A-HD mice. *: P < 0.05. (C) Representative color-coded images of ascending aorta generated from adherent MBVIS or MBIgG. Scale bar = 1 mm. (D) Quantitative analysis of signal intensities from (C). A-HD mice were raised with atorvastatin or placebo added into their daily hypercholesterolemic diet for 8 weeks. *: P < 0.05.