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. 2018 Feb 15;8(7):1940–1955. doi: 10.7150/thno.23674

Figure 3.

Figure 3

The relative genes expression level of chondrocytes cultured with SPS extracts. The expression of COL II gene (A, E), Aggrecan gene (B, F), SOX9 gene (C, G) and N-cadh gene (D, H) in chondrocytes post culturing with SPS extracts for 3 and 7 days, respectively.SPS extracts distinctly elevated the chondrocytes specified genes (COL II, SOX9 and N-cadh) expression within the concentration range of 3.125-50 mg/mL at day 3 and 7, as compared to that of CTR and TCP groups. Also, Aggrecan gene expression was significantly enhanced as compared to TCP extracts after co-culturing for 7 days within the whole experimental concentration range. The relative gene amount of CTR groups was set as 1, the value of expression gene was the fold change relative to CTR. Repeat number: n=3. (*p<0.05, **p<0.01, ***p<0.001).