Table 3.

The effect of aspirin on bronchoalveolar lavage (BAL) cytokines in healthy volunteers who inhaled lipopolysaccharide

BAL analyte	Placebo	Aspirin	Difference in median (95% CI)	p Value
TNFα (pg/mL)	106 (87–154)	78 (52–128)	33 (1.91 to 63.74)	0.03
IL-1β (pg/mL)	43 (26–99)	37 (19–55)	13 (−6 to 46)	0.17
IL-1β:IL-1Ra	0.02 (0.01–0.03)	0.01 (0.008–0.014)	0.01 (−.0.001 to 0.02)	0.07
IL-6 (pg/mL)	857 (606–1263)	648 (330–835)	258 (−40 to 526)	0.07
IL-8 (pg/mL)	448 (321–657)	346 (275–508)	102 (−40 to 253)	0.11
MCP-1 (pg/mL)	547 (412–1055)	502 (348–888)	83 (−168 to 363)	0.45
CRP (pg/mL)	332 (93–1140)	308 (114–824)	9 (−351 to 266)	0.99

IL, interleukin; TNFα, tumour necrosis factor α; MCP, Monocyte chemoattractant protein.