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. Author manuscript; available in PMC: 2018 Mar 19.
Published in final edited form as: Toxicol Appl Pharmacol. 2011 Aug 27;257(1):74–83. doi: 10.1016/j.taap.2011.08.020

Fig. 8.

Fig. 8

AICAR, metformin, and AMPK inhibitor-mediated electrophysiological changes in human iPSC-CMs. Human iPSC-CMs were plated on microelectrode arrays (MEA). MEA traces of serially increasing additions (0, 1, 2 mM) of (A) AICAR or (B) metformin that were recorded for 15 min at each concentration. MEA traces of serially increasing additions (0, 3, 30, 60 µM) of AMPK inhibitors (C) RO-9568 or (D) RO-3857 that were recorded for 15 min at each concentration, and each trace represents 10 s.”.