Anatomic differences exist among adult and children/adolescent articular cartilage, which are mainly related to direct vascular access from the subchondral bone to the cartilage layer. |
Prepubertal patients are equipped with a stronger cellular regeneration potential than adults; chondrocytes and stem cells have superior proliferation and differentiation properties. |
Chondral and osteochondral lesions are highly frequent among children and adolescents, most often related to sports injuries. |
The knee joint is the most often affected location. |
Osteochondral abnormalities are more frequent than chondral abnormalities. |
Traumatic patellar dislocations are the most frequent underlying abnormality resulting in joint surface abnormalities. |
Osteochondritis dissecans is the most frequent nontraumatic abnormality resulting in articular cartilage defects. |
Degenerative articular cartilage defects occur very seldom. |