Table 2.
Invasive hemodynamics and transthoracic echocardiography data.
| All patients (n = 4576) |
Patients with PH (n = 2689) |
|||||
|---|---|---|---|---|---|---|
| AAs (n = 586) | Caucasians (n = 3990) | P value | AAs (n = 428) | Caucasians (n = 2261) | P value | |
| Invasive hemodynamics | ||||||
| RA pressure (mmHg) | 10 ± 7 | 8 ± 6 | <0.001 | 12 ± 7 | 11 ± 6 | 0.002 |
| RV systolic pressure (mmHg) | 52 ± 21 | 45 ± 20 | <0.001 | 60 ± 20 | 57 ± 19 | 0.003 |
| Mean PAP (mmHg) | 34 ± 14 | 29 ± 14 | <0.001 | 40 ± 11 | 38 ± 11 | <0.001 |
| Mean PAWP (mmHg) | 17 ± 9 | 15 ± 8 | <0.001 | 19 ± 9 | 19 ± 8 | 0.79 |
| DPG (mmHg) | 6 ± 9 | 4 ± 9 | <0.001 | 8 ± 10 | 6 ± 11 | <0.001 |
| PVR (Woods units) | 4.0 ± 3.3 | 3.2 ± 3.3 | <0.001 | 4.8 ± 3.5 | 4.3 ± 3.9 | <0.001 |
| Cardiac index* (L/min/m2) | 2.8 ± 1.0 | 2.9 ± 1.0 | <0.001 | 2.6 ± 0.9 | 2.7 ± 0.9 | <0.001 |
| PA oxygen saturation (%) | 63 ± 11 | 68 ± 10 | <0.001 | 61 ± 11 | 64 ± 10 | <0.001 |
| Non-invasive hemodynamics | ||||||
| RV systolic pressure (mmHg) | 52 ± 23 | 46 ± 21 | <0.001 | 56 ± 24 | 51 ± 21 | 0.03 |
| TRV (m/s) | 3.3 ± 1.4 | 3.1 ± 0.8 | <0.001 | 3.5 ± 1.5 | 3.3 ± 0.8 | 0.22 |
| LA enlargement† (n (%)) | 299 (58) | 1911 (58) | 0.85 | 229 (61) | 1263 (65) | 0.15 |
| LV hypertrophy‡ (n (%)) | 168 (33) | 1041 (31) | 0.58 | 126 (33) | 634 (32) | 0.72 |
| LV ejection fraction§ (%) | 40 ± 19 | 47 ± 16 | <0.001 | 40 ± 19 | 45 ± 17 | 0.001 |
*
By Fick's method.
†
Anterior-posterior LA diameter > 40 mm.
‡
LV posterior wall thickness ≥ 12 mm.
§
By biplane Simpson's method.
RA, right atrial; RV, right ventricular; PAP, pulmonary arterial pressure; PAWP, pulmonary arterial wedge pressure; DPG, diastolic pressure gradient; PVR, pulmonary vascular resistance; AA, African American; PH, pulmonary hypertension; TRV, tricuspid regurgitant velocity; LA, left atrial; LV, left ventricular.