Table 2.
Summary statistics for baseline blood analyte measurements in cases versus controls.
| Analyte | Controls |
Cases |
||
|---|---|---|---|---|
| Mean | SD | Mean | SD | |
| Routine laboratory tests | ||||
| White blood cell count | 6.820 | 2.205 | 6.460 | 2.667 |
| Neutrophils | 4.371 | 2.227 | 3.892 | 2.245 |
| Lymphocytes | 1.646 | 0.413 | 1.717 | 0.467 |
| Monocytes | 0.582 | 0.124 | 0.565 | 0.185 |
| Creatinine | 101.300 | 33.330 | 107.400 | 28.640 |
| Haemoglobin | 126.700 | 10.478 | 121.600 | 12.076 |
| Platelets | 173.300 | 60.369 | 201.200 | 51.441 |
| C2 | 5212.300 | 1413.629 | 8723.800 | 5881.982 |
| C4b* | 3256.600 | 803.701 | 4010.560 | 783.449 |
| C5 | 90,399.900 | 33,301.216 | 1,11,882.100 | 59,453.757 |
| C5a | 4912.400 | 1177.679 | 5797.600 | 1877.560 |
| C9 | 4278.200 | 1147.436 | 3867.500 | 1123.123 |
| Factor D | 1120.800 | 11.361 | 1125.200 | 11.361 |
| MBL | 3527.278 | 4822.419 | 3443.722 | 3548.954 |
| C1q | 44.723 | 14.821 | 39.727 | 18.430 |
| C3** | 72.862 | 39.904 | 38.026 | 22.024 |
| C3b/iC3b | 350.452 | 125.924 | 428.461 | 242.295 |
| C4 | 544.511 | 199.553 | 459.482 | 136.783 |
| Factor B | 147.966 | 64.978 | 117.032 | 37.082 |
| Factor H | 313.943 | 86.472 | 266.233 | 93.867 |
| Factor I | 11,162.800 | 65.583 | 11,188.200 | 65.583 |
| Properdin | 18.307 | 6.733 | 17.135 | 8.379 |
| Cytokines/chemokines | ||||
| Eotaxin | 134.869 | 53.173 | 164.066 | 48.438 |
| GM-CSF** | 0.559 | 0.247 | 0.975 | 0.348 |
| IFN-α2 | 3.922 | 1.153 | 43.972 | 89.830 |
| IFN-γ | 3.170 | 1.613 | 22.689 | 29.608 |
| IL-10 | 6.121 | 5.843 | 6.338 | 6.361 |
| IL-12p40 | 4.790 | 1.110 | 23.614 | 37.595 |
| IL-12p70 | 2.914 | 0.201 | 13.216 | 32.658 |
| IL-13 | 6.597 | 10.657 | 97.719 | 275.431 |
| IL-15* | 2.575 | 0.145 | 5.420 | 6.703 |
| IL-17 | 2.466 | 0.134 | 5.281 | 6.155 |
| IL-1rα | 65.631 | 175.526 | 144.218 | 358.130 |
| IL-1b | 2.970 | 0.129 | 4.944 | 6.454 |
| IL-2 | 1.791 | 0.987 | 10.513 | 17.697 |
| IL-4 | 7.150 | 5.637 | 27.545 | 58.181 |
| IL-5 | 2.394 | 1.299 | 33.162 | 92.903 |
| IL-6 | 6.007 | 5.886 | 7.344 | 9.446 |
| IL-7 | 2.458 | 1.627 | 9.904 | 16.032 |
| IL-8 | 15.445 | 14.992 | 13.820 | 17.883 |
| IP-10 | 509.487 | 288.678 | 486.979 | 235.094 |
| MCP-1 | 627.069 | 139.342 | 562.416 | 269.159 |
| MIP-1α | 3.671 | 1.046 | 10.757 | 11.650 |
| MIP-1β* | 14.902 | 6.516 | 39.008 | 32.052 |
| TNF-α | 12.716 | 7.090 | 17.411 | 12.572 |
| Other inflammatory markers | ||||
| MMP-9 | 1,95,266.800 | 95,023.810 | 1,52,542.000 | 85,619.562 |
| hs-CRP | 5484.9 | 5035.4 | 2075.2 | 2362.8 |
*
p < 0.05; **p < 0.001. hs-CRP, high-sensitivity C-reactive protein; GM-CSF, granulocyte-macrophage colony-stimulating factor; IFN, interferon; IL, interleukin; IP-10, interferon gamma-induced protein 10; MBL, mannose-binding lectin; MCP-1, monocyte chemoattractant protein 1; MIP, macrophage inflammatory protein; MMP-9, matrix metallopeptidase-9; SD, standard deviation; TNF-α; tumour necrosis factor alpha.