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. 2018 Mar 19;13(3):e0192145. doi: 10.1371/journal.pone.0192145

Fig 6. TRAM-34 suppresses TGFβ1 induced pro-fibrotic gene expression.

Fig 6

Real-time RT-PCR showed that TRAM-34 treatment in primary human cornea fibroblast cells significantly suppressed TGFβ1 induced mRNA expression levels of (A) α-SMA (p<0.001) and (B) collagen I (p<0.001) at 24 hours (C) and 72 hours (D). Results are expressed as mean ± SEM (*p<0.05, **p<0.01, ***p<0.001).