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. 2018 Mar 19;13(3):e0193494. doi: 10.1371/journal.pone.0193494

Table 5. Antihypertensive drug classes and combinations according to BP control status.

CLASSES OF ANTIHYPERTENSIVE MEDICATIONS Blood pressure <140/90mmHg
N = 1,213
Blood pressure >140/90mmHg
N = 1,657
Total
N = 2870
P-values
Angiotensin Converting Enzyme Inhibitors 476 (39.2) 763 (46.0) 1239 (43.2) 0.0003
Angiotensin Receptor Blockers 312 (25.7) 472 (28.5) 784 (27.3) 0.10
Beta blockers 91 (7.5) 189 (11.4) 280 (9.8) 0.0005
Calcium Channel Blockers 961 (79.2) 1398 (84.4) 2359 (82.2) 0.0004
Diuretics 342 (28.2) 498 (30.1) 840 (26.3) 0.28
Centrally acting vasodilators (Methyldopa) 116 (9.6) 282 (17.0) 398 (13.9) <0.0001
Peripheral vasodilators (Hydrallazine) 7 (0.6) 35 (2.1) 42 (1.5) 0.0007
NUMBER OF ANTIHYPERTENSIVE MEDICATIONS
<0.0001
1 308 (25.4) 275 (16.6) 583 (20.3)
2 560 (46.2) 772 (46.6) 1332 (46.4)
3 220 (18.1) 429 (25.9) 649 (22.6)
4 43 (3.5) 107 (6.5) 150 (5.2)
5 9 (0.7) 18 (1.1) 27 (0.9)
6 0 (0.0) 1 (0.1) 1 (0.0)
7 0 (0.0) 1 (0.1) 1 (0.0)
No data available 73 (6.0) 54 (3.3) 127 (4.4)
Mean ± SD 1.90 ± 0.94 2.20 ± 0.95 2.07 ± 0.95 <0.0001
Median (IQR) 2 (1–2) 2 (2–3) 2 (2–3) <0.0001