Table 3. Pathology of spontaneous infection by E. coli in Rag2 and Il2rγ knockout W^sh/W^sh mice.

Accession #	Sex	Microbial Culture				Histologic lesions	FISH- E. coli
		E. coli	E. faecalis	E. faecium	S. xylosus
1512290008	Male	bl,n,lu,s,k	l	n		Pyelonephritis and interstitial pneumonia	ND
1512290026	Male	bl,n,lu,k	bl			Pyelonephritis	Kidney
1601050009	Female	bl				Metritis with macerated fetus, pyelonephritis, pneumonia, otitis media (bilateral), and epicarditis	Uterus and placenta
1601190003	Female	lu, li, k,u				Placentitis, metritis, and pneumonia	Uterus and placenta
1601260012	Female	lu,li,k,u	lu,k,u			Metritis, vaginitis myocarditis, meningoencephalitis, otitis media(unilateral), and pneumonia	Kidneys, uterus, vagina, and heart
1602030009	Female	lu,u	lu			Metritis, vaginitis, myocarditis, meningoencephalomyelitis, necrotizing hepatitis, unilateral otitis media and rhinitis	Uterus and placenta
1606150011	Male	k, br,bl	k, br	br		Nephropathy (intralesional bacteria)	Kidneys
1608160086	Female	k				Metritis and necrotizing suppurative pyelonephritis	Kidneys
1609230019	Female	u				Metritis, nephritis, interstitial pneumonia, and meningitis	Uterus
1609290016	Female	k	k,u		k,u	Pyelonephritis and interstitial pneumonia	ND
ND16-00081	Female	No bacterial isolation was performed, as the animals were found dead				Metritis with abundant intralesional bacteria and macerated fetus and pneumonia	Uterus and placenta
ND16-00082	Female					Cystitis and vaginitis with intralesional bacilli	Bladder and urogenital tract
ND16-00083	Female					Metritis and unilateral otitis media with intrahistiocytic bacteria	Uterus
ND16-00094	Female					Endometritis with macerated fetus and unilateral otitis media	ND
ND16-00164	Female					Pyelonephritis cystitis, endometritis, bilateral otitis media, rhinitis with intralesional bacteria, interstitial pneumonia, and meningitis	Uterus

blood-bl, brain-br, kidneys-k, lungs-lu, liver-li, nares-n, spleen-s and uterus-u and ND: Not detected.