Figure 2.

26 mm invasive ductal carcinoma in a 43 year-oldfemale. (a) Result of the breast segmentation algorithm superimposed to the first contrastenhanced image subtracted to the precontrast one. (b) Normalized maximum intensity projection over time of the breast region. (c) Tumour segmentation obtained by the CAD scheme superimposed to the maximum intensity projection over timeimage. Once the segmentation has been obtained, the radiologist selected the tumour to exclude false positive findings (red box). (d) Three-dimensional render of the mask of the tumour multiplied for the subtracted first contrastenhanced frame. The 2 most discriminative features of both GLCM and GLRLM algorithm are reported for this tumour. Pathological Complete Response (5/5), estrogen receptorstatus = 20%, progesterone receptor = status 25%, Ki67 = 30%, HER2 status = positive.