Table 4. Relationship between biofilm formation and the expression of efflux pumps and biofilm-related genes in A. baumannii in the presence of PMB at its sub-MICs.
A. baumannii | Factor | adeB | adeG | adeJ | ompA | bap | pgaA | abaI | |
---|---|---|---|---|---|---|---|---|---|
ATCC 19606 | Biofilm formation | 0.196 | 0.212 | −0.344 | 0.169 | 0.919** | 0.058 | 0.743** | |
MDRA | R2 | 0.754** | 0.131 | 0.046 | −0.027 | −0.087 | −0.155 | 0.464 | |
R3 | −0.121 | 0.418 | 0.450 | 0.948** | 0.953** | 0.344 | 0.138 |
Pearson correlation coefficients were calculated for ATCC19606, R2, and R3 strains cultured with different sub-MIC concentrations (0, 1/4, and 1/2 the MIC) of PMB.
** Significant at the level of 0.01 (2-tailed).