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. 2018 Mar 15;13:1539–1552. doi: 10.2147/IJN.S157519

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© 2018 Xia et al. This work is published and licensed by Dove Medical Press Limited

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(A) H&E, Ki67, and CD31 immunohistochemistry analysis of the tumors treated with saline, HA-Se-PEI, Se-PEI@siRNA, and HA-Se-PEI@siRNA. Yellow arrows were employed to highlight the immunohistochemical characteristics. Scale bar is 50 μm. (B) H&E analyses of heart, liver, spleen, lung, and kidney after treatment with saline, HA-Se-PEI, Se-PEI@siRNA, and HA-Se-PEI@siRNA, respectively. Scale bar is 50 μm.

Abbreviations: HA, hyaluronic acid; H&E, hematoxylin and eosin; PEI, polyethylenimine; Se, selenium; siRNA, small interfering RNA.

(A) H&E, Ki67, and CD31 immunohistochemistry analysis of the tumors treated with saline, HA-Se-PEI, Se-PEI@siRNA, and HA-Se-PEI@siRNA. Yellow arrows were employed to highlight the immunohistochemical characteristics. Scale bar is 50 μm. (B) H&E analyses of heart, liver, spleen, lung, and kidney after treatment with saline, HA-Se-PEI, Se-PEI@siRNA, and HA-Se-PEI@siRNA, respectively. Scale bar is 50 μm.

Abbreviations: HA, hyaluronic acid; H&E, hematoxylin and eosin; PEI, polyethylenimine; Se, selenium; siRNA, small interfering RNA.