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H5N1 pathogenesis in mammals. Virus and host features associated with H5N1 viruses which exhibit low or high virulence in the ferret model. Inset of lung histopathology is from Maines et al. (2005). Low titer generally represents ≤103 EID50/g or ml, high titer generally represents ≥105 EID50/g or ml (Maines et al., 2005).
