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. Author manuscript; available in PMC: 2018 Mar 19.
Published in final edited form as: Stem Cell Res. 2018 Jan 4;27:46–56. doi: 10.1016/j.scr.2017.12.016

Fig. 1. Intracranial germinomas resemble late PGCs.

Fig. 1

A. Timeline of germ cell development with expression patterns of germ line markers and epigenetic markers. *Early PGC expression pattern extrapolated from non-human primate data (Sasaki et al., 2016).

B. Immunofluorescence staining of intracranial germinomas for germ line markers, top panel: OCT4/cKIT/DAPI(merge), bottom panel: VASA/PLAP/DAPI(merge). Scale bars, 8 μm.

C. Immunofluorescence staining of intracranial germinomas for epigenetic markers, top panel: OCT4/5mC/DAPI (merge), bottom panel: OCT4/H3K27me3/DAPI(merge). Scale bars, 8 μm.