Figure 1. Qualitative comparison of AV-1451 among MAPT mutation carriers.

Each participant's AV-1451 tau PET scan is overlaid on their structural MRI in native space. The dynamic range for the color map is the same for each case, and reference examples of a control and a patient with AD are included for comparison in the same dynamic range (top left corner). Case number and mutation location are listed for each participant. AD = Alzheimer disease; CN = clinically normal; MAPT = microtubule-associated protein tau; SUVR = standardized uptake value ratio.