Table 1. Radioligand binding properties for [3H]-haloperidol and [3H]-(+)-pentazocine.
Kd and Bmax are determined using [3H]-haloperidol and [3H]-(+)-pentazocine in HEK 293T cell (second column) and guinea pig cortex (third column) membrane preparations.
| Compound | HEK 293T membrane | Guinea pig cortex | ||
|---|---|---|---|---|
| [3H]-haloperidol | Kd ± SEM (nM) | n | NA | |
| 7.87 ± 3.47 | 5 | |||
| Bmax ± SEM (fmol/mg) | n | |||
| 5847 ± 2221 | 5 | |||
| [3H]-(+)-pentazocine | Kd ± SEM (nM) | n | Kd ± SEM (nM) | n |
| 7.76 ± 0.52 | 3 | 5.18 ± 0.75 | 3 | |
| Bmax ± SEM (fmol/mg) | n | Bmax ± SEM (fmol/mg) | n | |
| 2080 ± 163 | 3 | 1091 ± 79 | 3 | |