Fig. 3. Cell apoptosis induced by knockdown of SLP-2 in NSCLC cells.
a A549, H460, H838, and H157 cells were treated with mock infection or with either AdSLP2i or AdCtrl at m.o.i. of 100. On day 5 post infection, cell cycle analysis showed a marked increase in the subG1 population of the AdSLP2i-treated cells. b A549, H460, H838, and H157 cells were treated with either AdSLP2i or AdCtrl at m.o.i. of 100. On day 3 post infection, degradation of poly-(ADP-ribose) polymerase (PARP) was clearly detected by western blotting analysis in all four AdSLP2i-treated cell lines