Table 2.
Receptor binding specificity |
||||
---|---|---|---|---|
Virus | HA 150 | α-2,3 | α-2,3 and α-2,6 | α-2,6 |
A/pigeon/Zhejiang/727097/2014 H5N1 | – | 256 | 256 | <2 |
A/Puerto Rico/8/1934 H1N1 | – | <2 | 128 | 256 |
rg6D2-WT | A | 512 | 128 | 256 |
rg6D2-MA (HA) | V | <2 | 256 | 1024 |
rg6D2-MA (HA/PA/PB2) | V | <2 | 512 | 1024 |
Hemagglutination titer of virus in three kinds of RBCs containing only SAα2,6 receptors, SAα2,6 receptors and SAα2,3 receptors, and only SAα2,3 receptors, respectively. Hemagglutination titers were calculated using the highest virus dilution.