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. 2018 Mar 19;8:4788. doi: 10.1038/s41598-018-23192-x

Table 4.

Mediators for unhealthy dietary pattern on fatty liver.

Indirect effect Direct effect Indirect/direct effect Mediator tests
Aroian Goodman Sobel
Systolic Blood Pressure(mmHg) 0.02 0.43 0.06 3.27 3.30 3.29
HOMA_B 0.27 0.41 0.65 5.42 5.45 5.43
HOMA_IR 0.01 0.41 0.03 5.48 5.50 5.49
Two Hour Insulin (µU/mL) 0.49 0.37 1.32 7.26 7.28 7.27
GGT (IU/L) 0.47 0.35 1.36 8.41 8.43 8.42
Total Cholesterol (mg/dL) 0.52 0.34 1.54 8.88 8.90 8.89
Two Hour Glucose (mg/dL) 0.35 0.34 1.06 8.95 8.98 8.96
HDL (mg/dL) 0.49 0.34 1.44 9.04 9.06 9.05
Diastolic Blood Pressure(mmHg) 0.07 0.34 0.22 9.05 9.08 9.06
LDL (mg/dL) 0.57 0.28 2.01 10.25 10.28 10.27
TG (mg/dL) 0.54 0.22 2.48 12.11 12.13 12.12
Weight (Kg) 0.64 0.18 3.58 12.65 12.67 12.66
FBS (mg/dL) 0.69 0.18 3.95 12.76 12.78 12.77
Age (years) 0.79 0.13 6.31 13.07 13.09 13.08
AST (IU/L) 0.63 0.15 4.30 13.50 13.52 13.51
ALT (IU/L) 0.67 0.14 4.93 13.51 13.53 13.52
BMI 0.56 0.15 3.73 13.55 13.57 13.56
Fast Insulin (µU/mL) 0.60 0.12 5.09 13.78 13.80 13.79
Waist (cm) 0.79 0.03 28.25 14.64 14.66 14.65

ALT, alanine aminotransferase; AST, Aspartate Aminotransferase; BMI, body mass index; FBS, Fasting Blood Sugar; GGT, gamma-glutamyl transferase; HDL, high-density lipoprotein; HOMA-IR, homeostasis model of insulin resistance; HOMA-β, Homeostatic model assessment of β cell function; LDL, low-density lipoprotein; TG, Triglyceride.