Fig. 1.

The S. coelicolor BldC regulon. a Chromosome-wide distribution of BldC binding sites identified by ChIP-chip analysis. DNA obtained from immunoprecipitation of BldC was labeled with Cy3 and hybridized to DNA microarrays together with a total DNA control labeled with Cy5. Data are plotted as Cy3/Cy5 ratios (y-axis), as a function of chromosome location (x-axis). b ChIP-chip data for nine selected BldC targets in WT S. coelicolor and the S. coelicolor ΔbldC mutant (blue and red dots, respectively). Plots span approximately 8 kb of DNA sequence. Gene names or identifiers (SCO numbers) are indicated below the arrows, which indicate gene orientation