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. Author manuscript; available in PMC: 2019 Jan 23.
Published in final edited form as: ACS Nano. 2017 Dec 12;12(1):109–116. doi: 10.1021/acsnano.7b07720

Figure 1.

Figure 1

Platelet membrane-coated nanoparticle (PNP) schematic and characterization. (a) PNPs express a variety of surface markers capable of targeting different components of atherosclerotic plaques, including activated endothelium, foam cells, and collagen. (b) Z-average size of bare PLGA cores, platelet membrane-derived vesicles, and PNPs as measured by dynamic light scattering (DLS) (n = 3, mean ± SD). (c) Surface zeta potential of bare PLGA cores, platelet membrane-derived vesicles, and PNPs as measured by DLS (n = 3, mean ± SD). (d) Z-average size of bare PLGA cores and PNPs in water or in PBS (n = 3, mean ± SD). (e) Transmission electron microscopy (TEM) image of bare PLGA cores (left) and PNPs (right) negatively stained with uranyl acetate (scale bars = 100 nm).