Table 3.
Normal | Chronic hepatitis | Cirrhosis | HCC | P value | |
IL-2 | 22.13 ± 2.21A1 | 16.28 ± 2.12B | 11.36 ± 0.95C | 10.24 ± 0.64C | < 0.001 |
IL-10 | 74.8 1 ± 1.34A | 98.46 ± 4.01AB | 104.11 ± 9.35B | 132.1 ± 14.26C | < 0.01 |
IL-12 | 0.06 ± 0.01A | 0.09 ± 0.01A | 0.15 ± 0.06A | 0.08 ± 0.01A | 0.393 |
IL-1β | 3.46 ± 0.15A | 6.48 ± 0.58A | 6.71 ± 2.39A | 21.38 ± 4.88B | < 0.001 |
IFN-α | 31.20 ± 0.67A | 32.28 ± 1.44A | 21.31 ± 1.01B | 18.49 ± 1.37B | < 0.001 |
IFN-γ | 20.47 ± 0.49A | 29.75 ± 0.68B | 17.51 ± 1.18C | 10.46 ± 0.56D | < 0.001 |
TNF-αR2 | 6.03 ± 0.07A | 13.25 ± 1.73A | 10.09 ± 0.97A | 47.42 ± 6.74B | < 0.001 |
Data are presented as mean ± SEM. 1Groups having the same letters in the same variable are statistically insignificant. HCC: Hepatocellular carcinoma; IFN: Interferon; IL: Interleukin; TNF: Tumor necrosis factor.