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. 2018 Mar 21;24(11):1228–1238. doi: 10.3748/wjg.v24.i11.1228

Table 3.

Levels of the studied cytokines among different studied groups

Normal Chronic hepatitis Cirrhosis HCC P value
IL-2 22.13 ± 2.21A1 16.28 ± 2.12B 11.36 ± 0.95C 10.24 ± 0.64C < 0.001
IL-10 74.8 1 ± 1.34A 98.46 ± 4.01AB 104.11 ± 9.35B 132.1 ± 14.26C < 0.01
IL-12 0.06 ± 0.01A 0.09 ± 0.01A 0.15 ± 0.06A 0.08 ± 0.01A 0.393
IL-1β 3.46 ± 0.15A 6.48 ± 0.58A 6.71 ± 2.39A 21.38 ± 4.88B < 0.001
IFN-α 31.20 ± 0.67A 32.28 ± 1.44A 21.31 ± 1.01B 18.49 ± 1.37B < 0.001
IFN-γ 20.47 ± 0.49A 29.75 ± 0.68B 17.51 ± 1.18C 10.46 ± 0.56D < 0.001
TNF-αR2 6.03 ± 0.07A 13.25 ± 1.73A 10.09 ± 0.97A 47.42 ± 6.74B < 0.001

Data are presented as mean ± SEM. 1Groups having the same letters in the same variable are statistically insignificant. HCC: Hepatocellular carcinoma; IFN: Interferon; IL: Interleukin; TNF: Tumor necrosis factor.