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. 2018 Mar 19;8:4829. doi: 10.1038/s41598-018-22862-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Analysis of the cell cycle of Jurkat (A) and MOLT-4 (B) leukemic cells 16 h after the application of scoulerine. Cells treated with 5 µM cisplatin were used as a reference compound. The pooled results of 1 of 3 independent experiments are shown. The bar graph represents the percentage of cells in the G1, S, and G2/M phase. Data are presented as mean values ± SD, n = 3. *Significantly different to control (P ≤ 0.05).