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. 2018 Mar 19;8:4773. doi: 10.1038/s41598-018-22923-4

Table 5.

Correlation between ICG-15 and different liver functional reserve models.

ICG-15 retention rate (%)
<10 10–15 15–20  > 20 p
ALBI (Mean ± SD) −3.81 ± 0.45 −3.69 ± 0.46 −3.53 ± 0.041 −3.31 ± 0.57 <0.001
APRI (Mean ± SD) 0.84 ± 1.23 1.26 ± 1.90 1.45 ± 1.47 1.66 ± 1.22 <0.001
CDS (Mean ± SD) 4.78 ± 1.46 5.02 ± 1.36 5.55 ± 1.65 5.98 ± 1.70 <0.001
FIB-4 (Mean ± SD) 2.62 ± 2.36 3.85 ± 3.95 4.67 ± 2.90 5.33 ± 2.80 <0.001
GUCI (Mean ± SD) 0.98 ± 1.50 1.44 ± 2.08 1.76 ± 1.84 2.05 ± 1.71 <0.001
Lok index (Mean ± SD) 0.39 ± 0.21 0.42 ± 0.19 0.50 ± 0.23 0.56 ± 0.24 <0.001
MELD (Mean ± SD) 7.83 ± 2.01 8.03 ± 1.73 8.49 ± 2.47 8.89 ± 2.89 <0.001
PALBI (Mean ± SD) −2.60 ± 0.35 −2.55 ± 0.32 −2.52 ± 0.26 −2.34 ± 0.40 <0.001
King’s score (Mean ± SD) 22.41 ± 31.00 36.74 ± 52.79 47.91 ± 52.07 49.98 ± 39.67 <0.001
CTP (Mean ± SD) 5.25 ± 0.53 5.29 ± 0.60 5.46 ± 0.68 5.80 ± 1.35 <0.001
Serum sodium (mmole/L; Mean ± SD) 139.71 ± 2.64 139.65 ± 2.61 139.40 ± 3.18 138.90 ± 2.74 0.181

ALBI, Albumin-bilirubin; APRI, Aspartate transaminase-to-Platelet ratio; CDS, Cirrhosis discriminant index; CTP, Child-Turcotte-Pugh score; FIB-4, Fibrosis-4 score; MELD, Model for End-stage liver disease; GUCI, Göteborg University Cirrhosis Index; PALBI, platelet-albumin-bilirubin; SD, standard deviation.