. Author manuscript; available in PMC: 2018 Mar 20.

Published in final edited form as: Acta Neuropathol. 2010 Jan 1;119(5):641–649. doi: 10.1007/s00401-009-0634-9

Table 3.

Associations between BRAF status and age, other genetic alterations, and histological features

Variable	P
Younger age	0.0584
1p	0.0666
19q	0.6174
9p21	0.7798
10q23	0.7531
17p13	0.2143
Oligodendroglial morphology	0.6704
Leptomeningeal spread	0.1188
Sharp tumor border	0.0296^*
High cellularity	0.8128
Nuclear atypia	0.9610
Mitoses	0.5208
Rosenthal fibres	0.4099
EGBs	0.9641

Multiple regression analysis identified a well-defined tumor border as significantly associated with BRAF rearrangement, plus trends toward rearrangements in younger patients as well as in tumors with intact 1p. Younger age and absence of 1p LOH showed a trend toward association with BRAF rearrangement

EGBs eosinophilic granular bodies

P < 0.05