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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Methods Mol Biol. 2018;1705:45–72. doi: 10.1007/978-1-4939-7465-8_3

Figure 6.

Figure 6

High-resolution X-ray crystallographic structures of the hP2Y12R with agonist 2-MeSADP (28) bound (purple carbon atoms, left), and comparison with a homology model of the hP2Y14R with potent nonnucleotide antagonist MRS4217 (37) bound (pink carbon atoms, right) [14].