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. 2018 Jan 24;4(3):FSO278. doi: 10.4155/fsoa-2017-0108

Figure 2. . Signaling pathway enrichment of the DEGs of four CRC stages.

Figure 2. 

MAPK signaling pathway (green line) and JAK-STAT signaling pathway (red line) had a negative correlation during colorectal cancer progression. Every significant hit in SPEED had an FDR <0.05.

DEG: Differentially expressed gene; CRC: Colorectal cancer; FDR: False discovery rate.