Figure 6. . Relationship between cell cycle and common up-regulated DEGs identified between S_I-S_IV of CRC (red color).

Activation, inhibition and undirected interactions are shown with solid green lines, solid red lines and dotted black lines, respectively. The cell cycle pathway was extracted from KEGG database.

DEG: Differentially expressed gene; S_I-S_IV: Stage 1 to Stage 4; CRC: Colorectal cancer; KEGG: Kyoto Encyclopedia of gene and genome.