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. 2018 Mar 13;9:497. doi: 10.3389/fimmu.2018.00497

Figure 12.

Figure 12

RNA and H3K4me3 depth at regions surrounding genome-wide association study variants. (A) RNA abundance at the TSS nearest the 143 SNPs curated from three studies and meta-analyses. This graph portrays the RNA at the TSS nearest the 143 SNPs (dark colors) compared with all other genes in the control samples (light bars). (B) H3K4me3 sequencing depth at the systemic lupus erythematosus (SLE) SNPs. This graph portrays all SLE SNPs binned according to p-value of SNP association (x-axis). The LD46 and META25 SNP sets represent top SNP sets from manuscripts (see Materials and Methods). The bars indicate sequencing depth in the controls at the three different cell types.