Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Mar 12;9:205. doi: 10.3389/fphys.2018.00205

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Hardy, Pervolaraki, Bernus and White.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

(A) APD25 restitution and (B) APD90 restitution for CON (°) and MCT (•) RV myoctes in the presence (dashed lines) or absence of 5 μM ranolazine. Ranolazine had no effect on APD25 or APD90. (C) APD25 restitution and (D) APD90 restitution for CON (°) and MCT (•) RV myocytes in the presence (dashed lines) or absence of prior exposure to BAPTA. BAPTA lengthened APD25 and reversed the restitution curve in MCT myocytes. In CON myocytes BAPTA reduced APD90 but did not affect APD restitution. n = 6–9 myocytes (A,B), n = 5–6 (C,D). ^*P < 0.05 vs. ranolazine or BAPTA, two way RM ANOVA.