Table 1.
CON | MCT | |
---|---|---|
Animals (n) | 6 | 6 |
Body weight (g) | 359 ± 5.7 | 275 ± 8*** |
Heart Weight (g) | 1.48 ± 0.06 | 1.63 ± 0.09 |
Lung Weight (g) | 1.82 ± 0.03 | 3.26 ± 0.31*** |
HW:BW (mg/g) | 4.13 ± 0.17 | 5.95 ± 0.38** |
LungW:BW (mg/g) | 5.07 ± 0.06 | 12.03 ± 1.40*** |
HW, heart weight; BW, body weight. MCT animals displayed cardiac hypertrophy and enlarged lungs, consistent with PAH.
P < 0.001,
P < 0.01,
P < 0.05, unpaired t-test.