Table 2.

Intra-class correlation coefficients (ICC) for estimates of tumour stroma ratio

	ICC	95% CI
Semi quantitative method A1	0.648	(0.533–0.762)
Semi quantitative method A2	0.611	(0.488–0.733)
Stereology (whole tumour area; continuous data)	0.592	(0.465–0.718)
Stereology (hot-spot sampled area; continuous data)	0.393	(0.236–0.550)
Stereology (whole tumour area; data categorized in 4 groups)	0.451	(0.301–0.601)
Stereology (hot-spot sampled area; data categorized in 4 groups)	0.322	(0.158–0.485)

Tumour stroma ratio (TSR) was estimated semi-quantitatively by conventional microscopy

Stereological TSR was estimated both in the whole available tumour area of the section and in the hot-spot sampled area

Abbreviations: CI confidence interval