Table 1.
Chromosomal translocations in hemangioendotheliomas and angiosarcoma
| Rearrangement | Involved gene(s) | Resultant phenotype | Reference no. |
|---|---|---|---|
| t(1;3)(p36.23;q25.1) | WWTR1, CAMTA1 | EHE | Tanas et al.,158 Anderson et al.,159 Errani et al.,160Patel et al.161 |
| t(11;X) | YAP1, TFE3 | EHE | Antonescu et al.162 |
| t(10;14) | PIGF | EHE | He et al.165 |
| t(7;19)(q22;q13) fusion | SERPINE1, FOSB | PHE | Walther et al.166 |
| 11p11.2-11q12.1 | NUP160, SLC43A3 | Angiosarcoma | Shimozono et al.169 |
WWTR1 WW domain containing transcription regulator 1, CAMTA1 calmodulin binding transcription activator 1, EHE epithelioid hemangioendothelioma, YAP1 the yes-associated protein 1, TFE3 transcription factor binding to IGHM enhancer 3, PlGF placental growth factor, SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1) member 1, FOSB FBJ murine osteosarcoma viral oncogene homolog B, PHE pseudomyogenic hemangioendothelioma, NUP160 nucleoporin 160 kDa, SLC43A3 solute carrier family 43, member 3