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. 2018 Mar 20;18:39. doi: 10.1186/s12935-018-0502-6

Table 1.

Relationship between miR-21 level and clinicopathologic characteristics in ESCC patients

Clinicopathologic characteristics Number of cases MiR-21 expression P
Low-miR-21 (n = 20) High-miR-21 (n = 43)
Age
 ≥ 60 45 11 28 0.213
 < 60 18 9 15
Gender
 Male 34 12 22 0.303
 Female 29 8 21
Size of primary tumor
 < 5 cm 29 9 20 0.538
 ≥ 5 cm 34 11 23
Tumor differentiation
 Highly differentiated 26 7 19 0.472
 Moderately differentiated 26 7 19
 Low differentiated 11 6 5
TNM stages
 I + II 29 16 13 0.004
 III + IV 34 4 30

TNM tumour, node and metastasis