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. 2018 Mar 20;18:303. doi: 10.1186/s12885-018-4213-0

Table 4.

Meta-regression circRNA associated with tumor type, sample size (> 50), and endogenous reference

Meta-Regression (Inverse Variance weights)
Var Coeff. Std. Err. p-value RDOR [95%CI]
Cte. 5.625 1.6550 0.0048
S 0.098 0.1198 0.4297
HCC −0.810 0.3463 0.0359 0.44 (0.21;0.94)
GC −0.402 0.2869 0.1844 0.67 (0.36;1.24)
size −0.741 0.5329 0.1876 0.48 (0.15;1.51)
ref −0.186 0.5345 0.7341 0.83 (0.26;2.64)

Tau-squared estimate = 0.0749 (convergence is achieved after 6 iterations)

Restricted Maximum Likelihood estimation (REML)

No. studies = 19

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Add 1/2 to all cells of the studies with zero